Can I take Folic acid and Vitamin C together?

Why this happens

Vitamin C (ascorbic acid) acts as an antioxidant that helps stabilise folate (folic acid) in the digestive tract, protecting it from oxidative degradation. This can slightly improve the absorption and stability of the folic acid.

You can safely take folic acid and vitamin C together. There is no need to separate the doses. If you are taking these as part of a pregnancy supplement or for anaemia, continue to follow the dosage instructions provided by your healthcare professional.

Vitamin B12 deficiency (Pernicious Anaemia)

Folic acid can mask the symptoms of vitamin B12 deficiency. If you have B12 deficiency, taking folic acid alone can allow serious nerve damage to progress even though your blood count appears normal. Your doctor must ensure your B12 levels are checked before or during treatment.

Kidney stones

High doses of vitamin C can increase the amount of oxalate in your urine, which significantly raises the risk of developing kidney stones, especially if you have had them before.

G6PD deficiency

If you have glucose-6-phosphate dehydrogenase (G6PD) deficiency, high doses of vitamin C can cause your red blood cells to break down (haemolysis).

Haemochromatosis

Vitamin C increases the absorption of iron from your food. If you have an iron-overload disorder like haemochromatosis, you should avoid high-dose supplements.

Alcohol

It is best to avoid or strictly limit alcohol while taking folic acid. Alcohol interferes with the way your body absorbs and uses folic acid, which can make the treatment less effective. Chronic alcohol consumption is a common cause of folate deficiency.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.