Can I take Hydroxocobalamin and Lipitor together?

Why this happens

These medications are processed by different pathways in the body. Hydroxocobalamin is a synthetic form of Vitamin B12 used to treat deficiencies, while Lipitor is a statin used to lower cholesterol. They do not interfere with each other's absorption, metabolism, or effectiveness.

You can continue to take both medications as prescribed by your doctor. It is helpful to take them at the same time each day to help you remember, though they do not need to be taken together for them to work. If you experience any new or unusual muscle pain while taking Lipitor, you should always inform your doctor, regardless of other supplements you are taking.

Pregnancy

You must not take Lipitor if you are pregnant or planning to become pregnant, as it may harm the unborn baby. Use effective contraception while taking it.

Muscle problems - Lipitor

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness. This is particularly important if you also feel unwell or have a high temperature.

Hypokalaemia (low potassium)

When starting treatment for severe vitamin B12 deficiency, your potassium levels can drop rapidly as your body produces new red blood cells. This can be dangerous for your heart and may require monitoring by your doctor.

Alcohol

It is best to avoid or strictly limit alcohol while taking these medicines. For Lipitor, regular heavy drinking increases your risk of liver problems and muscle damage. For Hydroxocobalamin, heavy alcohol consumption can interfere with the absorption of B12 and may worsen the underlying deficiency being treated.

Grapefruit and Grapefruit Juice

You should avoid drinking large quantities of grapefruit juice (more than 1.2 litres a day) or eating grapefruit while taking Lipitor. Grapefruit contains compounds that can increase the level of the medicine in your blood, which raises your risk of serious side effects, such as muscle damage (rhabdomyolysis).

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.