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Can I take Lactulose and Naproxen bp together?

Drug interaction guide

There is no known direct interaction between lactulose and naproxen. It is generally safe to take these two medicines together.

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Why this happens

Lactulose is a sugar-based laxative that works locally in the bowel to soften stools. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) used for pain and inflammation. They are processed by the body through different pathways and do not interfere with how the other works.

What you should do

You can take both medicines as prescribed. However, always ensure you drink plenty of water while taking lactulose to help it work effectively and to prevent dehydration, which can sometimes increase the risk of kidney strain when taking NSAIDs like naproxen.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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