Can I take Lansoprazole and Tamsulosin together?

Why this happens

Lansoprazole is a proton pump inhibitor (PPI) used to reduce stomach acid, and tamsulosin is an alpha-blocker used to help with urinary symptoms. They are processed by different pathways in the liver and do not interfere with how the other is absorbed or cleared from the body.

You can continue to take both medicines as prescribed by your doctor. As with any medication, if you notice any new or unusual side effects, you should mention them to your GP or pharmacist.

Severe diarrhoea

Lansoprazole can increase your risk of serious bowel infections. If you develop severe or persistent watery diarrhoea, or a fever, contact your doctor immediately and do not take anti-diarrhoeal medicine.

Lupus (SLE) or skin reactions

Contact your doctor if you develop a skin rash, especially in areas exposed to the sun, as lansoprazole can cause a rare but serious autoimmune skin reaction.

Cataract or glaucoma surgery

If you are planning to have eye surgery, tell your surgeon you are taking tamsulosin. It can cause 'Floppy Iris Syndrome', which may lead to complications during the procedure.

Postural hypotension (dizziness when standing)

Tamsulosin can cause a sudden drop in blood pressure when you stand up, especially after the first dose. Sit or lie down until the feeling passes if you feel dizzy or faint.

Alcohol

It is best to avoid or strictly limit alcohol while taking these medicines. Alcohol can increase the risk of stomach irritation when taking lansoprazole. For tamsulosin, alcohol can increase the risk of feeling dizzy or faint, especially when you stand up, as both can lower your blood pressure.

Food (Timing)

Lansoprazole works best if you take it at least 30 minutes before food. Taking it with or after food can make it less effective at reducing stomach acid.

Caffeine (Coffee, Tea, Energy Drinks)

Lansoprazole is often prescribed for acid reflux. Caffeine can trigger or worsen reflux symptoms by relaxing the muscle at the base of the food pipe, which may make your medicine less effective at managing your symptoms.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.