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Can I take Losartan and Magnesium glycinate together?

Drug interaction guide

Taking magnesium glycinate with losartan may lead to an extra drop in your blood pressure. While this is often harmless, it can sometimes make you feel dizzy, lightheaded, or faint, especially when standing up quickly. Additionally, both substances can slightly affect how your kidneys handle potassium, though this is rarely a problem for people with healthy kidneys.

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Why this happens

Both losartan and magnesium work to relax your blood vessels and lower blood pressure. When used together, their effects can add up (an additive effect). Magnesium also has a very mild effect on how the kidneys process minerals, similar to how losartan works.

It is generally safe to take these together, but you should monitor your blood pressure regularly. To avoid dizziness, try to get up slowly from a sitting or lying position. If you feel very dizzy, fatigued, or notice a fluttering heartbeat, mention it to your doctor. It is also a good idea to have your kidney function and potassium levels checked during your routine blood tests.

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Pregnancy

You must not take losartan if you are pregnant or planning to become pregnant. It can cause serious injury or death to an unborn baby, particularly if used in the second and third trimesters.

High potassium (Hyperkalaemia)

Losartan can increase potassium levels in your blood. You should avoid using potassium supplements or salt substitutes containing potassium while taking this medicine, as levels can become dangerously high.

Angioedema (Severe swelling)

Seek immediate medical help if you experience swelling of the face, lips, tongue, or throat. This is a rare but serious allergic reaction that can block your airway.

Alcohol

Drinking alcohol while taking losartan can increase the blood-pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you first.

Potassium-rich foods and salt substitutes

Losartan can increase the levels of potassium in your blood. You should avoid using salt substitutes that contain potassium (often labelled as 'low sodium' salts) and speak to your doctor before significantly increasing your intake of potassium-rich foods like bananas, spinach, or sweet potatoes. High potassium levels can affect your heart rhythm.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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