Can I take Losartan and Solifenacin together?
Drug interaction guide
Originally published 14 Mar 2026
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There is no direct interaction between losartan and solifenacin that would change how the drugs are absorbed or processed by your body. However, both medications can occasionally cause side effects like dizziness or a fast heartbeat. Taking them together might slightly increase the chance of feeling lightheaded, especially when standing up quickly.
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Why this happens
Losartan lowers blood pressure, and solifenacin (an antimuscarinic) can sometimes cause a slight increase in heart rate or a drop in blood pressure when standing. While they work on different systems, their combined effect on your circulation could lead to mild dizziness.
What you should do
Back to contentsIt is generally safe to take these two medicines together. To stay safe, take care when getting out of bed or standing up from a chair until you know how the combination affects you. If you experience severe dizziness, fainting, or a very fast heartbeat, contact your doctor.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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