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Can I take Magnesium and Ramipril together?

Drug interaction guide

Taking magnesium supplements at the same time as ramipril may slightly lower the amount of ramipril your body absorbs. Additionally, both substances can lower your blood pressure; taking them together might cause your blood pressure to drop lower than intended, potentially making you feel dizzy or light-headed.

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Why this happens

Magnesium can physically bind to ramipril in the digestive tract, making it harder for the medicine to enter your bloodstream. Furthermore, both magnesium and ramipril have blood-pressure-lowering effects (pharmacodynamic synergy), which can have an additive effect on your circulation.

What you should do

To ensure your ramipril works effectively, try to space the doses apart by at least 2 hours. If you feel dizzy, faint, or unusually tired when taking both, speak to your doctor or pharmacist. It is also a good idea to have your blood pressure checked regularly.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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