Skip to main content

Can I take Metformin and Quetiamine together?

Drug interaction guide

Taking quetiapine may make your metformin less effective at controlling your blood sugar levels. This can lead to higher blood sugar (hyperglycaemia).

Continue reading below

Why this happens

Quetiapine is an antipsychotic medication that can interfere with how your body handles insulin and sugar. It can cause the body to become less sensitive to insulin or reduce the amount of insulin produced, which directly opposes the blood-sugar-lowering effects of metformin.

What you should do

You should monitor your blood sugar levels more frequently when starting, stopping, or changing the dose of quetiapine. If you notice your blood sugar readings are consistently high, or if you experience increased thirst or frequent urination, contact your doctor. They may need to adjust your metformin dose.

Continue reading below

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.