Can I take Lixiana and Morphine together?

Why this happens

Morphine slows down the movement of the digestive system (gastric emptying). This can delay how quickly Lixiana enters your bloodstream. Additionally, strong painkillers like morphine can sometimes mask the pain of internal bleeding or, in some cases, increase the risk of stomach irritation which may lead to bleeding when combined with a blood thinner.

What you should do

You can take these medicines together, but you should be extra vigilant. Watch for signs of unusual bleeding, such as bruising easily, nosebleeds, bleeding gums, or dark, tarry stools. If you are prescribed morphine for long-term use, discuss this with your doctor to ensure your dose of Lixiana is still providing the right level of protection. Always take your Lixiana exactly as prescribed.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.