Can I take Milk thistle extract and Vitamin c together?
Drug interaction guide
Originally published 14 Mar 2026
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There are no known significant interactions between milk thistle (silymarin) and vitamin C (ascorbic acid) when taken together at standard doses.
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Why this happens
Milk thistle and vitamin C are processed by the body through different pathways. Vitamin C is water-soluble and primarily excreted by the kidneys, while the active components of milk thistle are mainly processed by the liver and excreted through bile. They do not interfere with each other's absorption or effectiveness.
What you should do
Back to contentsIt is generally safe to take these two supplements together. Always follow the dosage instructions on the product packaging and inform your doctor or pharmacist about all the supplements you are taking, especially if you have underlying liver or kidney conditions.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
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Taking these two medicines together can cause your blood pressure to drop too low (hypotension). You may also experience a very slow heart rate or feel excessively tired, dizzy, or faint. There is also an increased risk of your kidneys not working as well as they should or your blood potassium levels becoming too high.

Treatment and medication
Can I take Amlodopine and Aspirin 300 together?
Taking aspirin with amlodipine may slightly increase the risk of stomach irritation or bleeding, and high doses of aspirin (like 300mg) can sometimes make blood pressure medication slightly less effective.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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