Skip to main content

Can I take Naproxen and Quetiamine together?

Drug interaction guide

Taking naproxen and quetiapine together may increase your risk of internal bleeding, particularly in the stomach or intestines. It can also increase the risk of bruising or bleeding from the gums. Additionally, both medications can affect your kidney function, and using them together might put extra strain on the kidneys.

Continue reading below

Why this happens

Naproxen is an anti-inflammatory (NSAID) that can thin the blood slightly and irritate the stomach lining. Quetiapine, while an antipsychotic, can also interfere with how platelets (the cells that help your blood clot) work. When combined, these effects add up, making bleeding more likely. Both drugs also reduce blood flow to the kidneys.

What you should do

You should use this combination with caution. Watch for signs of stomach irritation, such as indigestion, stomach pain, or dark, tarry stools. If you notice unusual bruising or bleeding that won't stop, contact your doctor. Your doctor may want to monitor your kidney function with occasional blood tests if you take these long-term.

Continue reading below

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.