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Can I take Naproxen bp and Quinine together?

Drug interaction guide

Taking naproxen and quinine together may increase the risk of bleeding or bruising. It can also increase the chance of developing stomach irritation or ulcers. Additionally, both medications can occasionally affect your heart rhythm, and taking them together might slightly increase this risk.

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Why this happens

Naproxen is an NSAID that thins the blood slightly by affecting platelets and can irritate the stomach lining. Quinine can also lower platelet counts in some people, leading to an additive effect on bleeding risk. Both drugs have the potential to affect the electrical activity of the heart (prolonging the QT interval), though this is rare at standard doses.

What you should do

Use this combination with caution. If you have a history of stomach ulcers, heart rhythm problems, or bleeding disorders, speak to your doctor before taking them together. Seek medical advice if you notice unusual bruising, black tarry stools, or if you feel dizzy or notice a fluttering sensation in your chest.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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