Can I take Naproxen bp and Uribel together?

Why this happens

Naproxen is an NSAID that can irritate the stomach lining and affect kidney function. Uribel contains phenyl salicylate; because both drugs inhibit prostaglandins (chemicals that protect the stomach and support kidney blood flow), their effects can add together, increasing the risk of side effects like stomach pain or reduced kidney clearance.

What you should do

Use this combination with caution. If you have a history of stomach ulcers, kidney problems, or asthma, speak to your doctor before taking them together. Take these medications with food to protect your stomach. If you notice any unusual bruising, black tarry stools, or persistent stomach pain, stop taking them and contact your doctor immediately.

Important precautions

Asthma or Aspirin Sensitivity

Do not take this medicine if you have asthma or a history of allergic reactions to aspirin or other NSAIDs, as it can trigger a life-threatening asthma attack or severe allergic reaction.

Stomach Ulcers or Bleeding

This medicine significantly increases the risk of stomach ulcers and internal bleeding. Seek immediate medical help if you experience black, tarry stools or vomit blood.

Glaucoma or Urinary Retention

This medicine can dangerously increase eye pressure in people with glaucoma and worsen symptoms of an enlarged prostate or bladder obstruction.

Food and drink warnings

Alcohol

Drinking alcohol while taking naproxen can increase the risk of stomach irritation, stomach ulcers, and internal bleeding. It is best to limit or avoid alcohol.

Food (General)

Naproxen should ideally be taken with or just after food or a glass of milk. This helps to protect your stomach lining and reduce the risk of indigestion or stomach pain.

Acidic foods and drinks (e.g., citrus fruits, cranberry juice, fizzy drinks)

Uribel works best when the urine is slightly acidic. However, very acidic foods or drinks can sometimes worsen the bladder irritation you are treating. Additionally, some components of Uribel (like methenamine) require a specific urine pH to work effectively; consult your pharmacist before significantly changing your intake of acidic juices.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.