Can I take Oxypro and Paracetamol together?

Why this happens

Oxypro (oxycodone) is an opioid painkiller that works on the central nervous system, while paracetamol works differently to reduce pain signals and fever. Because they work through different pathways, they can be used at the same time (additive effect) to manage more severe pain.

What you should do

It is safe to take these together as long as you do not exceed the maximum daily dose of paracetamol (usually 4000mg or eight 500mg tablets in 24 hours). Always check your Oxypro packaging; if it is a combination product that already contains paracetamol, do not take extra paracetamol. If you have liver or kidney problems, consult your doctor before combining these medicines.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.