Can I take Simvastatin and Vitamin b12 together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known harmful interaction between simvastatin and vitamin B12. It is generally safe to take these two together.
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Why this happens
Simvastatin is a cholesterol-lowering medication (statin) processed primarily by the liver, while vitamin B12 is a water-soluble vitamin absorbed in the gut and used for nerve and blood health. They do not interfere with each other's absorption, metabolism, or effectiveness.
What you should do
You can continue taking both as prescribed. You do not need to separate the doses or change the time of day you take them. Always inform your doctor or pharmacist of all supplements you are taking.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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