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Cefixime for infection

Suprax

Before you take cefixime, make sure your doctor knows if you have ever had an allergic reaction to any other antibiotic.

Complete the full course, even if you feel your infection has cleared up.

The most common side-effect is diarrhoea, which is usually mild and soon passes. If it becomes severe or lasts for more than 24 hours, you should speak with your doctor.

At a glance

  • Cefixime is an antibiotic used to treat bacterial infections.

  • It is taken once or twice daily, with or without food.

  • Always finish the full course of tablets, even if you feel better.

  • Tell your doctor if you have kidney problems or have had allergic reactions to other antibiotics.

  • Common side-effects include diarrhoea, nausea, tummy discomfort, and headache.

  • Seek urgent medical help for signs of an allergic reaction like rash or difficulty breathing.

Continue reading below

About cefixime

Type of medicine

A cephalosporin antibiotic

Used for

Infections

Also called

Suprax®

Available as

Tablets

Cefixime is a broad-spectrum antibiotic, which means that it is active against a wide variety of bacteria. It is used to treat short-term (acute) bacterial infections such as urinary tract infections, chest and throat infections, and ear infections. Cefixime treats an infection by killing the bacteria that are causing it.

Some people who are allergic to penicillin antibiotics may not be able to take cefixime, so make sure your doctor knows if you have ever had an allergic reaction to any other antibiotic.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking cefixime it is important that your doctor knows:

  • If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have had a bad reaction to a penicillin or cephalosporin antibiotic.

  • If you have any problems with the way your kidneys work.

  • If you are pregnant, trying for a baby or breastfeeding. (Although cefixime is not known to be harmful to babies, it is still important that you tell your doctor if you are expecting or breastfeeding a baby.)

  • If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

Continue reading below

  • Before you start taking cefixime, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about the antibiotic and a full list of side-effects which you may experience from taking it.

  • You should take cefixime exactly as your doctor tells you to. The usual dose for adults and for children over 10 years of age, is 1 or 2 tablets daily. You will be told whether to take this as a single dose each day, or as two doses, morning and evening. The dose for younger children is calculated from their age or weight. Your doctor will tell you what dose is right for you (or your child), and this information will be printed on the label of the pack to remind you.

  • You can take cefixime before or after food. Swallow the tablets whole with a drink of water. If you are taking more than one dose a day, space your doses out evenly throughout the day.

  • Keep taking the antibiotic until the course is finished unless you are told to stop by your doctor. Taking the full course is important (even if you feel your infection has cleared up) in order to prevent the infection from coming back.

  • If you forget to take a dose, take one as soon as you remember. Try to take the correct number of doses each day.

  • Some people develop thrush (redness and itching in the mouth or vagina) after taking a course of antibiotics. If you think you have thrush speak with your doctor or pharmacist for advice.

  • If you are using oral combined hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are recommended for a time if you have sickness (vomiting) or diarrhoea which lasts for more than 24 hours. If you need further advice about this, speak with your doctor or pharmacist.

  • If you are having an operation or any other medical treatment, tell the person carrying out the treatment that you are taking an antibiotic. This is because cefixime may interfere with the results of some tests to check for sugar in urine.

  • Cefixime may stop the oral typhoid vaccine from working. If you are having any vaccinations, make sure the person treating you knows that you are taking this antibiotic.

Continue reading below

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with cefixime. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

C

efixime side-effects

What can I do if I experience this?

Diarrhoea

Drink plenty of water to replace any lost fluids. If the diarrhoea continues for longer than 24 hours, or becomes severe or contains blood, let your doctor know

straightaway

Feeling sick (nausea), tummy (abdominal) discomfort, indigestion

Stick to simple foods. If you are not already doing so, try taking your doses after meals to see if it helps

Headache

Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know

Feeling dizzy

Do not drive and do not use tools or machines until you feel well

Important: if you develop an itchy rash, swollen face or mouth, or have difficulty breathing, these can be signs that you are allergic to the antibiotic. Do not take any more cefixime and speak with your doctor or go to your local accident and emergency department straightaway.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist for further advice.

  • Keep all medicines out of the reach and sight of children.

  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Report side effects to a medicine or vaccine

If you experience side effects, you can report them online through the Yellow Card website.

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Unsure about mixing medicines?

Check for possible interactions between medicines, supplements and foods before taking them together.

Frequently asked questions

Are there any specific foods or drinks I should avoid while taking cefixime?

The article states that you can take cefixime before or after food, which suggests there are no specific foods or drinks you need to avoid. However, it also mentions that if you experience feeling sick or abdominal discomfort, sticking to simple foods and taking doses after meals might help.

What should I do if I accidentally take an extra dose of cefixime?

If you suspect that you or someone else might have taken an overdose of cefixime, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty, to help healthcare professionals understand what has been taken.

Can cefixime affect the effectiveness of other medicines I am taking, especially over-the-counter ones?

It is important to inform your doctor, and a pharmacist if you buy any medicines, about all the medicines you are taking, including those available without a prescription and herbal or complementary medicines. This is because cefixime may interact with some other medicines, and they can advise you if they are safe to take together.

What should I do with any leftover cefixime after my course is finished?

You should not keep out-of-date or unwanted medicines. When you have finished your course of cefixime, or if you have any left over, you should take it to your local pharmacy. They will dispose of it for you safely.

How long does cefixime take to work against the infection?

The article states that cefixime treats an infection by killing the bacteria that are causing it. However, it does not specify an exact timeframe for when you will feel the effects or how long it takes for the antibiotic to completely clear the infection. It does stress the importance of taking the full course, even if you feel your infection has cleared up, to prevent it from returning.

Further reading and references

Continue reading below

About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

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