Fluoxetine

About fluoxetine

**What is fluoxetine used for?**

Fluoxetine is a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI). It is used to treat depression, bulimia nervosa, and obsessive-compulsive disorder (OCD).

Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine increase the amount of circulating serotonin available in your brain. Altering the balance of the chemicals in the brain can help improve symptoms of depression, eating disorders like bulimia, and OCD.

Depression can develop for no apparent reason, or it can be triggered by a life event such as a relationship problem, a bereavement, or an illness. Bulimia nervosa is an eating disorder. People with bulimia nervosa have episodes of binge eating which they counteract by making themselves sick. Obsessive-compulsive disorder (OCD) is a condition where you have recurring and persistent ideas that make you do repetitive actions.

Side effects of fluoxetine

The most common side effects of fluoxetine are:

• Feeling sick.

• Being sick (vomiting).

• Diarrhoea.

• Indigestion.

• Dry mouth.

• Headache..

• Feeling more anxious, nervous, or agitated

• Feeling restless or shaky.

• Feeling dizzy, tired or weak.

• Blurred vision.

• Trouble sleeping.

• Reduced sexual drive (libido).

• Yawning.

• Sweating.

You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

How to manage fluoxetine side effects

If you experience any other symptoms that you think may be due to this medicine, speak with your doctor or pharmacist for further advice.

Who should not take fluoxetine?

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking fluoxetine it is important that your doctor knows:

• If you are pregnant, trying for a baby or breastfeeding.

• If you have any problems with the way your liver works.

• If you have a heart condition.

• If you have epilepsy.

• If you have high blood sugar levels (diabetes mellitus).

• If you have an eye problem called glaucoma.

• If you have ever had a bleeding disorder.

• If you have ever had abnormally 'high' moods, called mania.

• If you are being treated with electroconvulsive therapy (ECT).

• If you have ever had an allergic reaction to a medicine.

• If you have taken an antidepressant known as a monoamine-oxidase inhibitor (MAOI) within the previous two weeks.

• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

How to take fluoxetine

• Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about fluoxetine and will provide you with a full list of the side effects which you may experience from taking it.

• Take fluoxetine exactly as your doctor tells you to - the directions will be printed on the label of the pack to remind you of what your doctor said.

  • As a guide, if you are being treated for depression or OCD, it is usual to be prescribed 20 mg (one capsule or 5 ml liquid medicine) as a once-daily dose. Your dose may later be increased.

  • For people being treated for bulimia, the usual daily dose is 60 mg (three capsules or 15 ml liquid medicine).

• You can take fluoxetine before or after food. If you have been given capsules, swallow them whole with a drink of water - do not chew or open the capsules.

  • If you have difficulty swallowing capsules, let your doctor know, as you could be prescribed liquid medicine or soluble tablets to take instead.

  • Try to take your doses at the same time of day, each day.

• If you have been given soluble (dispersible) tablets, they can be swallowed whole with a drink of water or dissolved in half a glass of water before taking. Do not crush or chew the tablets.

• If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

Getting the most from your treatment

• You may feel that fluoxetine is not working for you straightaway. It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it, even if you feel it is not helping.

• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

• While you are taking fluoxetine, you may have thoughts about harming yourself or ending your life. These thoughts may also be associated with your condition. It is very important that you tell your doctor about this if it happens.

• Do not stop taking fluoxetine unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.

• You should expect that a course of treatment will last for several months. This is normal and helps to prevent your symptoms from recurring.

• If you drink alcohol, ask your doctor for advice. Your doctor is likely to recommend that you do not drink alcohol while you are on fluoxetine.

• If you have diabetes, you may need to check your blood glucose more frequently, as fluoxetine may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.

• If you buy any medicines, check with a pharmacist that they are safe to take with fluoxetine. This is because several medicines which are available from general retail outlets can interfere with this treatment.

  • In particular, do not take the herbal remedy St John's wort, and ask for advice before buying any anti-inflammatory painkillers.

• A few people taking fluoxetine find that their skin is more sensitive to sunlight than normal. Until you know how your skin reacts, use a sun cream with a high sun protection factor (SPF) in strong sunlight.

• There are several types of antidepressants and they differ in their possible side effects. If you find that fluoxetine does not suit you then let your doctor know, as another may be found that will.

How to store fluoxetine

• Keep all medicines out of the reach and sight of children.

• Store in a cool, dry place, away from direct heat and light.

• The oral liquid medicine usually lasts for one month after first opening. After this time make sure you have a fresh supply.

Important information about all medicines

Frequently asked questions

Can you drink alcohol on fluoxetine?

You should avoid or limit alcohol when taking fluoxetine, as it can worsen side effects and affect mood. However, an occasional small drink is unlikely to cause serious harm.

Is fluoxetine used more for anxiety or depression?

Fluoxetine is used for both depression and some anxiety disorders, such as obsessive compulsive disorder (OCD). Your doctor will decide if it’s suitable based on your symptoms.

Can you overdose on fluoxetine?

Yes, it’s possible to overdose on fluoxetine. Taking more than the prescribed dose can cause serious side effects such as nausea, tremors, rapid heartbeat or, in severe cases, seizures. Seek urgent medical help if you think you or someone else may have taken too much.

Does fluoxetine make you gain weight?

Fluoxetine can affect weight. Some people may notice slight weight gain, others may lose weight, and many experience no change at all. Changes can be linked to appetite, lifestyle, and how the medication affects mood.