
Who is eligible for weight loss injections?
Peer reviewed by Dr Colin Tidy, MRCGPAuthored by Victoria RawOriginally published 22 May 2025
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Weight loss injections have been making headlines and trending across social media. You may have even seen advertisements promoting medicines that accelerate weight loss. At first glance, it might seem anyone can buy and use these treatments. However, that's not the case - you must meet specific medical criteria to be eligible for them.
In this article:
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Who is eligible for weight loss injections?
You may be prescribed weight loss medicine if you have certain health conditions that have not improved with lifestyle changes, such as diet and exercise alone.
They include:
Obesity - if you have a body mass index (BMI) of 35 or over.
A weight-related health condition - such as type 2 diabetes, high blood pressure (hypertension), high cholesterol, heart disease, sleep apnoea, or polycystic ovary syndrome (PCOS), along with a BMI between 30 and 34.9.
Your BMI threshold for eligibility may be lower if you're of Asian, Black or Middle-Eastern descent.
There are currently four types of weight loss injections approved for use in the UK.
These are:
Orlistat - taken as a capsule, it blocks about a third of the fat you consume from being absorbed.
Liraglutide (also known as Saxenda) - a daily injection that helps you feel fuller for longer and reduces hunger.
Semaglutide (also known as Wegovy) - a weekly injection that promotes fullness and curbs your appetite.
Tirzepatide (also known as Mounjaro) - a weekly injection that helps reduce hunger and increase feelings of fullness.
Who shouldn't use weight loss injections?
You should never take weight loss medicine unless it has been prescribed by your doctor and, in some cases, your pharmacist. They can assess whether it is an appropriate treatment for you.
There are several important factors to consider before starting weight loss medicine. Depending on your health and circumstances, you may be more susceptible to certain side effects, which could make these medicines unsafe and lead to serious health consequences.
Some weight loss medicines are not safe to use during pregnancy or breastfeeding, or if you have certain health conditions - such as liver or kidney issues. They may also reduce the effectiveness of oral contraceptives.
Dr Hazel Parkinson, a GP based in Long Itchington, UK, explains that weight loss medicines are only prescribed to patients who meet the outlined criteria.
She says: "Weight loss injections are not a quick fix, and strict criteria exist for good reason. These medicines can be life-changing for the right person, but they're not suitable for everyone."
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Lifestyle changes vs weight loss injections
You should always talk to your doctor before considering any type of weight loss medicine. Healthcare professionals are the only people qualified to determine whether weight loss medicines are appropriate for you.
As mentioned above, weight loss medicine may be prescribed if lifestyle changes have not led to improvements in your weight and health. Your doctor will first recommend practical steps to help you lose weight - such as improving your diet and increasing your physical activity.
Beyond medical advice, they can connect you with local weight loss groups for support or arrange sessions with a qualified trainer through a local active health team.
Are weight loss injections available on the NHS?
If, despite focused efforts to improve your diet and exercise routine, you haven’t lost significant weight, you can discuss your situation with your doctor for further options.
Weight loss medicine on the NHS requires a referral from your doctor, a weight management service, or a specialist clinic, and is subject to strict eligibility criteria. You may not be able to begin taking weight loss medicine immediately due to waiting lists and the urgency of your case compared to others.
Alternatively, you can opt for private treatment, through clinics or pharmacists, which offers quicker access to consultations but typically involves higher costs.
Parkinson says: "In private practice, eligibility is also broader. But it's still vital these medicines are used under medical supervision, with full assessment of lifestyle, mental health, and nutritional needs."
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Healthy habits for people on weight loss medicine
Starting weight loss medicine can be an option if traditional weight loss methods have not proved effective despite consistent effort.
However, it’s important to continue following a healthy diet and aim for the recommended 150 minutes of exercise each week.
Medicines like Mounjaro and orlistat require you to follow a balanced, reduced-calorie diet and maintain regular exercise both before starting treatment and throughout - as well as after - to support lasting results.
Some weight loss medicines are not intended for long-term use, so it’s important to adopt healthy lifestyle habits to help prevent weight regain after your treatment ends.
Some side effects of these medicines can worsen if you don’t monitor your diet. For example, orlistat may cause bowel-related issues if your diet is too high in fat.
Your progress during the first few months of weight loss treatment will be closely monitored and assessed by a healthcare professional, depending on the medicine you’re taking. Based on how your body responds, your healthcare provider will guide you through the next steps in your weight loss journey.
Article history
The information on this page is peer reviewed by qualified clinicians.
Next review due: 22 May 2028
22 May 2025 | Originally published
Authored by:
Victoria RawPeer reviewed by
Dr Colin Tidy, MRCGP

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