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Can I take Alcohol and Citalopram together?

Drug interaction guide

Drinking alcohol while taking citalopram can make you feel much more drowsy, dizzy, or sleepy than usual. It can also impair your coordination, reaction times, and judgement. Additionally, alcohol can worsen the symptoms of depression or anxiety that the citalopram is meant to treat, potentially making the medication less effective over time.

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Why this happens

Both alcohol and citalopram affect the central nervous system (the brain). When used together, they have an 'additive effect,' meaning they combine to increase the sedative (calming/sleepy) impact on the brain. While alcohol does not significantly change the levels of citalopram in your blood, it changes how your brain responds to the drug.

What you should do

It is best to avoid alcohol, especially when you first start taking citalopram or if your dose has recently increased. Once you know how the medication affects you, you may be able to have a very small amount of alcohol, but be aware that your tolerance will be much lower. If you do choose to drink, do so in moderation, stay at home or in a safe place, and do not drive or operate machinery.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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