Can I take Azithromycin and Terbutaline together?
Drug interaction guide
Originally published 24 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking azithromycin and terbutaline together may increase the risk of developing an irregular heart rhythm. While this is rare, it can be serious. Symptoms to watch out for include heart palpitations (a fluttering feeling in the chest), dizziness, fainting, or sudden shortness of breath.
In this article:
Continue reading below
Why this happens
Both of these medicines have the potential to slightly affect the electrical activity of your heart (specifically, they can prolong the 'QT interval'). When used at the same time, their effects can add together, making an irregular heartbeat more likely.
What you should do
Speak to your doctor before taking these together, especially if you have a history of heart problems or low levels of potassium or magnesium in your blood. If your doctor has prescribed both, follow their instructions closely. Seek immediate medical help if you feel your heart is beating irregularly, or if you feel faint or dizzy.
Continue reading below
Important precautions
Heart rhythm disorders (Long QT syndrome)
Azithromycin can cause serious changes to your heart rhythm. You must inform your doctor if you have a history of heart palpitations, a slow heart rate, or a family history of 'Long QT syndrome'.
Diabetes
Terbutaline can cause your blood sugar levels to rise. If you have diabetes, you may need to monitor your blood glucose more frequently when starting treatment or increasing your dose.
Food and drink warnings
Caffeine (Coffee, tea, energy drinks, cola)
Terbutaline is a stimulant that can increase your heart rate. Consuming caffeine while taking this medicine may increase the risk of side effects like a racing heart, palpitations, or feeling shaky/jittery.
Food (General)
If you have been prescribed azithromycin in capsule form, you must take it at least 1 hour before food or 2 hours after food. Food significantly reduces the absorption of the capsules. Note: This does not apply to azithromycin tablets or liquid suspension, which can be taken with or without food.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Amytriptaline and Nustendi together?
There is no known direct interaction between amitriptyline and Nustendi (bempedoic acid and ezetimibe). However, amitriptyline can sometimes cause side effects like muscle pain or weakness, which are also rare side effects of the ingredients in Nustendi. Taking them together might slightly increase the risk of these symptoms being noticed.

Treatment and medication
Can I take Ibuprofen and Ibuprofen lysine together?
Taking these two medications together is effectively taking a double dose of the same medicine. This significantly increases your risk of serious side effects, such as stomach ulcers, internal bleeding, and kidney problems.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
24 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.