Can I take Amytriptaline and Nustendi together?

Why this happens

Amitriptyline is an antidepressant that can occasionally cause muscle-related side effects. Nustendi contains bempedoic acid and ezetimibe; bempedoic acid is known to increase the levels of certain cholesterol medications (statins) which cause muscle pain, though it does not directly interact with amitriptyline's metabolism in the liver.

What you should do

It is generally safe to take these two medications together. However, you should inform your doctor if you experience any unexplained muscle pain, tenderness, or weakness while taking this combination. Always ensure your doctor is aware of all medications you are taking.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.