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Can I take Amlopadine and Ramipril together?

Drug interaction guide

Taking amlodipine and ramipril together can cause your blood pressure to drop lower than if you took either medicine alone. While this is often the goal of treatment, it can sometimes make you feel dizzy, lightheaded, or faint, especially when you stand up quickly. It may also increase the risk of your kidneys not working as well as they should.

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Why this happens

Both medicines work to lower blood pressure but in different ways: amlodipine relaxes the muscles in your blood vessel walls, while ramipril blocks a hormone that causes blood vessels to tighten. Because they both target the blood vessels, their effects add together (an additive effect).

What you should do

This is a very common and effective combination, but you should be careful when first starting them or when your dose is increased. To avoid dizziness, get up slowly from a sitting or lying position. Your doctor will likely perform regular blood tests to check your kidney function and potassium levels. If you feel very dizzy or faint, contact your doctor.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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