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Can I take Atenolol and Ramipril together?

Drug interaction guide

Taking these two medicines together can cause your blood pressure to drop lower than intended, especially when you first start the combination or when your dose is increased. This might make you feel dizzy, lightheaded, or faint, particularly when standing up quickly. There is also a small risk that the combination could affect your kidney function or increase the levels of potassium in your blood.

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Why this happens

Both medicines work to lower blood pressure but in different ways: atenolol is a beta-blocker that slows the heart rate, while ramipril is an ACE inhibitor that relaxes blood vessels. When used together, their effects add up (an additive effect). Both can also impact how the kidneys filter blood and manage potassium levels.

What you should do

It is very common for doctors to prescribe these two medicines together, but you should be monitored closely. When starting this combination, take your first dose at bedtime to avoid dizziness. Stand up slowly from a sitting or lying position. Your doctor will likely perform regular blood tests to check your kidney function and potassium levels. If you feel severely dizzy or faint, contact your GP.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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