Can I take Atorvastatin and Nustendi together?
Drug interaction guide
Originally published 24 Jan 2026
Meets Patient’s editorial guidelines
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Taking these two medicines together can increase the amount of atorvastatin in your blood. This makes it more likely that you will experience side effects, particularly muscle pain, tenderness, or weakness (a condition called myopathy). In rare cases, this can lead to serious kidney problems.
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Why this happens
Nustendi is a combination tablet containing two medicines: bempedoic acid and ezetimibe. The bempedoic acid part of Nustendi can block the way your body normally clears atorvastatin from your system. This causes the level of atorvastatin to rise higher than intended.
What you should do
You can take these medicines together, but your doctor should limit your dose of atorvastatin to no more than 20mg per day (or 40mg if you are already taking that dose without issues). If you experience any unexplained muscle pain, tenderness, or weakness, contact your doctor immediately.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Can I take Amlopadine and Atorvastatin together?
Taking amlodipine and atorvastatin together can increase the amount of atorvastatin in your blood. This may increase the risk of side effects, particularly muscle pain, tenderness, or weakness (a condition called myopathy). In rare cases, this can lead to a more serious muscle breakdown called rhabdomyolysis.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
24 Jan 2026 | Originally published
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