Can I take Atorvastatin and Reisha together?

Why this happens

Both atorvastatin and Reishi mushroom are processed by the liver. Reishi contains compounds that may interfere with the liver enzymes (specifically CYP450 enzymes) responsible for breaking down atorvastatin. If the liver cannot clear the medication effectively, levels of atorvastatin in the blood may rise, increasing the risk of toxicity. Additionally, both substances can individually affect liver function, potentially leading to an additive effect on liver enzymes.

What you should do

You should consult your doctor or pharmacist before combining Reishi mushroom with atorvastatin. If you decide to take both, be alert for signs of liver issues (such as yellowing of the eyes or skin, dark urine, or upper stomach pain) or unexplained muscle pain, tenderness, or weakness. Your doctor may wish to monitor your liver function more closely through routine blood tests.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.