Can I take Betahistine and Citalopram together?
Drug interaction guide
Originally published 24 Jan 2026
Meets Patient’s editorial guidelines
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There are no known significant interactions between betahistine and citalopram. It is generally considered safe to take these two medicines together.
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Why this happens
These medicines work in different ways and are processed by different pathways in the body. Betahistine acts on histamine receptors in the inner ear to treat vertigo, while citalopram increases serotonin levels in the brain to treat depression or anxiety. They do not interfere with each other's absorption or metabolism.
What you should do
You can take both medicines as prescribed by your doctor. As with any new combination, monitor how you feel and speak to your pharmacist or GP if you notice any unusual side effects, such as increased dizziness or nausea.
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Important precautions
Asthma
Betahistine can cause narrowing of the airways, which may worsen asthma symptoms or cause breathing difficulties. Patients with asthma should be closely monitored.
Peptic Ulcer Disease
Betahistine can increase stomach acid production, which may worsen existing stomach ulcers or cause them to recur. Use with caution if you have a history of indigestion or ulcers.
Heart Rhythm Disorders (Long QT Syndrome)
Citalopram can affect the electrical activity of the heart. It must be avoided if you have a heart rhythm problem called 'long QT syndrome' or if you are taking other medicines that affect heart rhythm.
Food and drink warnings
Alcohol
While alcohol does not have a direct chemical interaction with citalopram, it is generally advised to avoid drinking alcohol while taking antidepressants. Alcohol can worsen depression and increase the sedative side effects (drowsiness or dizziness) of the medication.
Food (General)
You should ideally take betahistine with or after a meal. This helps to prevent minor stomach upsets, which are a common side effect of this medicine.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
24 Jan 2026 | Originally published

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