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Can I take Calcium and Ciprofloxacin together?

Drug interaction guide

Taking calcium at the same time as ciprofloxacin can significantly reduce the amount of the antibiotic that gets into your bloodstream. This means the medicine may not work properly to clear your infection.

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Why this happens

Calcium binds to the ciprofloxacin in your stomach or gut, forming a 'complex' that is too large for your body to absorb. Instead of entering your blood, the medicine simply passes through your system.

What you should do

Do not take calcium supplements, antacids containing calcium, or large amounts of dairy products at the same time as ciprofloxacin. You should take ciprofloxacin at least 2 hours before or 6 hours after taking any calcium-containing products.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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