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Can I take Reishi and Royal sun together?

Drug interaction guide

Both Reishi and Royal Sun (Agaricus blazei) mushrooms can thin the blood and lower blood sugar levels. Taking them together may increase the risk of bruising, bleeding, or your blood sugar dropping too low (hypoglycaemia).

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Why this happens

These mushrooms have 'additive' effects. This means they work in similar ways to slow down blood clotting and improve how the body handles sugar. When combined, these effects can become much stronger than intended.

What you should do

It is usually fine to take these together, but you should monitor yourself for signs of low blood sugar (such as feeling shaky, sweaty, or dizzy) and watch for unusual bruising or bleeding. If you are scheduled for surgery or are taking prescribed blood thinners or diabetes medication, speak to your doctor before combining these supplements.

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Using other medicines?

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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