Can I take Sertraline and Alcohol together?

Why this happens

Sertraline and alcohol both affect the central nervous system (the brain). When taken together, they have an 'additive effect', meaning they enhance each other's sedative properties. Alcohol can also interfere with how the brain processes serotonin, the chemical that sertraline is designed to balance.

What you should do

It is best to avoid drinking alcohol altogether while taking sertraline, especially when you first start the medication or if your dose has recently increased. If you do choose to drink, keep it to a very small amount, drink slowly with food, and be aware that one drink may affect you much more strongly than usual. Do not drive or operate machinery if you have been drinking.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.