Pelvic inflammatory disease is an infection of the internal reproductive organs of a woman. It usually involves the womb (uterus), Fallopian tubes and sometimes the ovaries. It may also affect the areas of the lower tummy (pelvis) around these organs. It is important to treat it with antibiotics to prevent complications.
What is pelvic inflammatory disease?
If you have pelvic inflammatory disease (PID), you have an internal infection, which has usually passed into the womb (uterus) and its surrounding organs from the vagina or neck of the womb (cervix). In most cases, the infection is passed on through sex (a sexually transmitted infection - STI).
Causes: sexually transmitted infections
A common cause of PID is from a sexually transmitted infection (STI). The germs (bacteria) are passed on when you have sex. Chlamydia and gonorrhoea are the most commonly found causes of PID. A mixture of chlamydia plus gonorrhoea sometimes occurs. Another type of bacterium called Mycoplasma genitalium is also a common cause. Sometimes the bacteria can be in the neck of the womb for some time without causing symptoms. When they travel into the womb you become unwell. This is why you might develop PID weeks or months after having sex with an infected person.
Some cases of PID are not due to an STI. The vagina normally contains many different bacteria. These are usually harmless and are not passed on by sexual contact. However, these bacteria sometimes cause PID. This is more of a risk after having a baby, or after a procedure such as inserting an intrauterine contraceptive device (coil).
How do you contract PID? How does PID affect fertility? Does PID cause bleeding? How do you treat PID? All your questions answered.
What are the symptoms of pelvic inflammatory disease?
- Pain in the lower tummy (abdomen), called the pelvic area, is the most common symptom of PID. It can range from mild to severe.
- Other symptoms that may also occur include:
Symptoms may develop quickly. You can become quite ill over a few days. Sometimes symptoms are mild and develop slowly. For example, you may just have a mild abdominal pain that may 'grumble on' for weeks. In some cases no symptoms develop and you do not know that you are infected. However, you are still at risk of complications even if you have no symptoms at first.Pelvic inflammatory disease
"The level of pain would just get worse to the point where it crippled me and I would spend days in bed. These symptoms were also accompanied by very painful heavy irregular periods, as well as spotting."— Laura, 30, from London, What it's like to have pelvic inflammatory disease
Who develops pelvic inflammatory disease?
It is not known how many women develop PID each year, and it is probably often not picked up. It most commonly develops in women aged between 15 and 24 years. The risk of developing PID is higher if you have had:
- A recent change of sexual partner. The risk goes up with the number of partners.
- A previous episode of PID or STI.
- A recent abortion.
- A recent operation or procedure on the womb (uterus).
- An intrauterine contraceptive device (coil) or intrauterine system inserted recently.
What tests may be done?
If PID is suspected, a small sample (swab) of discharge is usually taken from the neck of your womb (cervix). This is to test for any germs (bacteria). A swab from the urethra (where you pass urine from) and blood and urine tests may also be taken. These are to look for infecting bacteria or the effects of infection.
Sometimes the swabs and tests may not show any bacteria. So to help confirm a diagnosis of PID, other tests may be needed. For example, a blood test may show up some inflammation/infection, or an ultrasound scan may be able to show inflamed Fallopian tubes. Other scans are sometimes done.
If your doctor has particular concerns, they may need to look inside your tummy (abdomen) to see your womb (uterus) and tubes. Whilst you are under general anaesthetic a thin telescope (laparoscope) is pushed through your tummy wall. This is called a laparoscopy. Laparoscopy is not routinely needed to diagnose PID.
PID may not be diagnosed for some time if symptoms are mild, or do not occur at first.
A pregnancy test is also usually done in women suspected of having PID. This is because an ectopic pregnancy can sometimes be confused with PID, as some of the symptoms are similar. An ectopic pregnancy is a pregnancy that develops in a Fallopian tube and can cause serious problems.
What are the possible complications?
Complications do not develop in most cases if PID is diagnosed and treated early. Possible complications include one or more of the following:
- Difficulty becoming pregnant (infertility). PID can cause scarring or damage to the Fallopian tubes. This can occur whether or not the PID caused symptoms.
- An increased risk of a pregnancy developing in a Fallopian tube (an ectopic pregnancy) if you become pregnant. This is due to damage to the Fallopian tube by the infection. If you have had PID and become pregnant, you have about a 1 in 10 chance that it will be ectopic.
- Persistent pain may develop. This often includes pain during sex.
- The risks of developing some complications of pregnancy (such as miscarriage, premature birth and stillbirth) are increased in pregnant women with untreated PID.
- Reiter's syndrome. This is an uncommon cause of arthritis and eye inflammation. It is an uncommon complication of PID. It is thought to be due to the immune system 'over-reacting' to pelvic infection in some cases.
- A collection of pus (an abscess) sometimes develops next to the womb (uterus) if the infection is severe.
You are less likely to develop complications if you begin treatment within 2-3 days of symptoms starting. This may be possible if symptoms develop quickly. However, some women with PID have mild symptoms, or no symptoms at all. The infection may progress for quite some time before it is diagnosed or treated.
What is the treatment for pelvic inflammatory disease?
The usual treatment is a course of antibiotics for at least two weeks. Sometimes your doctor may feel you need to be in hospital for treatment. This is advisable if your temperature is very high (higher than 38°C) or there are signs of a collection of pus (an abscess).
Two different antibiotics are often prescribed. This is to cover the range of possible germs (bacteria) that can cause PID. You may also be given an injection of an antibiotic first, followed by a course of one or two antibiotic tablets for two weeks. There are a number of different regimes to treat PID. It is important to take the full course of treatment. Treatment will usually be started as soon as possible if PID is suspected. This might sometimes be even before the results of samples (swabs) or other tests are available. This is because the earlier the treatment, the better the outlook, and the lower the risk of future fertility problems.
Tell your doctor if you are (or may be) pregnant. This may affect the choice of antibiotic.
Occasionally, an operation is needed. For example, to drain an abscess if one develops (which is very uncommon).
You should not have sex until both you and your sexual partner have finished treatment.
Does my partner need to be treated?
Yes. Also, any other sexual partner within the previous six months should be tested for infection. If you have not had sex within the previous six months then your latest sexual partner (however long ago the relationship was) should be tested and treated. A course of antibiotics is usually advised whether or not infection is found on testing. This is because:
- Many cases of PID are caused by chlamydia. It is often passed on during sex.
- Men often have no symptoms with chlamydia, but can still pass on the infection.
- The test for chlamydia is not 100% reliable. Treatment makes sure that any possible infection which may have been missed by the tests is cleared.
- If your sexual partner is infected and not treated, chlamydia may be passed back to you again after you are treated.
Can pelvic inflammatory disease be prevented?
If you are sexually active and under 25 years old, you should be tested for chlamydia every year or when you change your sexual partner. There are lots of local places where you can have a test - young people's clinics, youth clubs, colleges, contraception/family planning clinics, your GP surgery, sexual health (genitourinary) clinics and some pharmacies. The test is simple and painless. It is totally voluntary and completely confidential. You can take the test yourself and you do not need to be examined. You will be asked to give a urine sample or, in some places, to take a sample (swab) from the lower vagina (a cotton wool bud is used to wipe the area).
Will it happen again?
About 1 in 5 women who have PID have a further episode. This is often within two years. Reasons why this may occur include:
- If your sexual partner was not treated. You are then likely to get the infection back again.
- If you did not take the antibiotics properly, or for long enough. The infection may then not clear completely, and may flare up again later.
- If you change your sexual partner and do not practise 'safer sex' by using condoms.
- Some women are more prone to infection once their womb (uterus) or tubes have been damaged by a previous episode of PID.
The risk of developing complications such as infertility or persistent pelvic pain is greatly increased with repeated episodes of PID.
Further reading and references
2018 United Kingdom National Guideline for the Management of Pelvic Inflammatory Disease; British Association for Sexual Health and HIV (BASHH) 2018
Pelvic inflammatory disease; NICE CKS, April 2015 (UK access only)
Ross J, Guaschino S, Cusini M, et al; 2017 European guideline for the management of pelvic inflammatory disease. Int J STD AIDS. 2018 Feb29(2):108-114. doi: 10.1177/0956462417744099. Epub 2017 Dec 4.
Savaris RF, Fuhrich DG, Duarte RV, et al; Antibiotic therapy for pelvic inflammatory disease. Cochrane Database Syst Rev. 2017 Apr 244:CD010285. doi: 10.1002/14651858.CD010285.pub2.
Bartlett EC, Levison WB, Munday PE; Pelvic inflammatory disease. BMJ. 2013 May 23346:f3189. doi: 10.1136/bmj.f3189.
Das BB, Ronda J, Trent M; Pelvic inflammatory disease: improving awareness, prevention, and treatment. Infect Drug Resist. 2016 Aug 199:191-7. doi: 10.2147/IDR.S91260. eCollection 2016.
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