Fluid overload
Peer reviewed by Dr Krishna Vakharia, MRCGPLast updated by Dr Hayley Willacy, FRCGP Last updated 31 Oct 2022
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In this series:Congestive heart failureLoop diuretics
Fluid overload means that there is too much fluid in the body. The increased level of fluid results in an excessive amount of fluid flowing around the circulatory system. This can overwork the heart and lead to heart failure.
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Fluid overload symptoms
The excess fluid circulating around the body can cause waterlogging of the lungs, leading to breathlessness. The medical term for this is acute pulmonary oedema. 'Acute' means 'of quick onset'.
Alternatively the overloading process can occur over a longer period of time and cause additional symptoms like swelling in the lower leg and high blood pressure. The type of swelling that occurs in the legs is called pitting oedema. This means that when the swelling is pressed with a finger, it leaves an indentation, or a 'pit'.
Can fluid overload cause death?
This depends on the cause of the fluid overload - how serious it is and and whether it can be treated.
Even if the fluid overload is not caused by a heart condition, if it is not treated the extra pressure on the heart eventually leads to heart failure. This causes tiredness, shortness of breath and swelling of the legs and feet. Heart failure is a complex condition which can result in a lower life expectancy for some.
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What causes fluid overload?
The heart and kidneys interact to control fluid volume and the sodium content in the body. This system is quite complex.
Treatment with fluid can be a cause. It is sometimes difficult to calculate how much fluid the body needs. This can happen when nutritional fluid or blood is given through a drip. The risk of overload may be increased if you are elderly, you have had a major injury or operation, or your kidneys or heart do not work as well as they should,
Sometimes the problem is not so much extra fluid as too much sodium. Sodium is a chemical that occurs naturally in the body and needs to be at a certain level in the blood and other body fluids. If too much sodium is given, the body will retain water to try to correct this.
People with heart failure may have fluid overload,
People whose kidneys suddenly stop working properly (acute kidney injury or chronic kidney disease) can be similarly affected.
How is fluid overload diagnosed?
A number of conditions produce signs and symptoms that resemble fluid overload, and these need to be excluded. These conditions include:
Lung problems, such as blood clots, infections, asthma.
Heart problems, such as inflammation of the covering of the heart (pericarditis).
Problems with the venous circulation or lymphatic circulation.
Metabolic disorders causing a low protein level in the blood (hypoproteinaemia).
Liver disease.
Thyroid disease.
Kidney disease.
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Will I need any tests?
It's not surprising that with all these conditions to rule out you may need several tests. These may include:
Heart tests: heart tracing (electrocardiogram, or ECG) and ultrasound scanning of the heart (echocardiogram, or echo).
Blood tests to check your kidney function, blood count, liver function, blood gases.
A special test for heart failure, called B-type natriuretic peptide (BNP).
Charts to check how much you drink and pee and any weight changes in response to treatment.
How to treat fluid overload
The treatment depends on your symptoms and the underlying cause. The possible treatments include:
'Water tablets' (diuretics): see the leaflets on Loop Diuretics and Thiazide Diuretics for more information.
Mineralocorticoid/aldosterone receptor antagonists (MRAs) - eg, spironolactone and eplerenone - like diuretics, also prevent the build-up of fluid.
In some situations you may be advised to restrict fluid or salt intake.
You may be asked to weigh yourself daily.
Other treatments such as dialysis may also be needed for severe fluid overload.
What is the outlook for fluid overload?
This depends on the underlying cause and how well you were before the fluid overload occurred. For example:
If the fluid overload was due to a problem with your heart, the outlook (prognosis) depends on how treatable your heart condition is.
If the fluid overload resulted from being given too much fluid during intravenous treatment, the outlook will depend on the reason why you needed a drip in the first place.
If you were given it because you had just had a simple operation but were well beforehand, the outlook should be good once the overload is corrected.
However, if intravenous treatment was given because you had a serious problem such as extensive burns, correcting the overload may be more complicated.
Further reading and references
- Messmer AS, Zingg C, Muller M, et al; Fluid Overload and Mortality in Adult Critical Care Patients-A Systematic Review and Meta-Analysis of Observational Studies. Crit Care Med. 2020 Dec;48(12):1862-1870. doi: 10.1097/CCM.0000000000004617.
- Perez Nieto OR, Wong A, Lopez Fermin J, et al; Aiming for zero fluid accumulation: First, do no harm. Anaesthesiol Intensive Ther. 2021;53(2):162-178. doi: 10.5114/ait.2021.105252.
- Raina R, Sethi SK, Wadhwani N, et al; Fluid Overload in Critically Ill Children. Front Pediatr. 2018 Oct 29;6:306. doi: 10.3389/fped.2018.00306. eCollection 2018.
- Zoccali C, Moissl U, Chazot C, et al; Chronic Fluid Overload and Mortality in ESRD. J Am Soc Nephrol. 2017 Aug;28(8):2491-2497. doi: 10.1681/ASN.2016121341. Epub 2017 May 4.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 30 Oct 2027
31 Oct 2022 | Latest version
9 Jul 2017 | Originally published
Authored by:
Dr Laurence Knott
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