Can I take Amlodipine and Chemydur 60xl together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking amlodipine and Chemydur 60XL (isosorbide mononitrate) together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, lightheaded, or faint, especially when you stand up quickly from a sitting or lying position.
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Why this happens
Both medicines work by relaxing and widening your blood vessels to lower blood pressure and improve blood flow to the heart. When used together, their effects add up, which can lead to an excessively low blood pressure (hypotension).
What you should do
Back to contentsYou can take these medicines together if they have been prescribed by your doctor, but you should be cautious. To prevent dizziness, try to get up slowly when standing. If you feel very dizzy, have a persistent headache, or feel like you might faint, sit or lie down immediately and contact your doctor. Your doctor may want to monitor your blood pressure more closely when you first start this combination.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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