Can I take Mirtazapine and Stexerol D3 together?

Why this happens

Mirtazapine is an antidepressant that works on brain chemicals, while Stexerol D3 is a supplement used to maintain vitamin D levels. They are processed by different pathways in the body and do not interfere with how the other works.

What you should do

You can continue taking both medications as prescribed by your doctor. As with any supplement, it is best to take them at the same time each day to maintain consistent levels in your body.

Important precautions

Depression and mental health disorders

Mirtazapine can increase thoughts of self-harm or suicide, particularly when you first start taking it or when your dose is changed. You must tell someone you trust that you are taking this medicine and seek medical help immediately if your mood worsens or you have distressing thoughts.

Low white blood cell count (Agranulocytosis)

Mirtazapine can rarely cause a serious drop in white blood cells. You must contact a doctor immediately if you develop signs of infection, such as a high fever, severe sore throat, or mouth ulcers.

Hypercalcaemia (High blood calcium)

You must not take Stexerol D3 if you have high levels of calcium in your blood or urine, or if you have severe kidney stones, as it can dangerously worsen these conditions.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol while taking mirtazapine. Both alcohol and mirtazapine cause drowsiness and can affect your coordination; combining them significantly increases these effects, making you feel very sleepy and increasing the risk of accidents.

Caffeine (Coffee, Tea, Energy Drinks)

Caffeine can counteract the sedative effects of mirtazapine, potentially making the medicine less effective for sleep or increasing feelings of anxiety.

High-fat meals

Stexerol D3 is a fat-soluble vitamin. It is best absorbed by your body when taken with a meal that contains some fat (such as dairy, eggs, or avocado).

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.