Can I take Apixaban and Losartin together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between apixaban and losartan. They are often prescribed together for patients with heart conditions. However, both medications can affect your kidneys or blood pressure, so your doctor will likely monitor your kidney function and blood pressure regularly.
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Why this happens
Apixaban is an anticoagulant (blood thinner) and losartan is an Angiotensin II Receptor Blocker (blood pressure medication). They are processed by different pathways in the body and do not interfere with how the other works.
What you should do
You can take these two medicines together as prescribed. Ensure you attend your regular blood pressure checks and blood tests for kidney function. If you notice any unusual bruising or bleeding (common with apixaban) or feel dizzy when standing up, inform your doctor.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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