Can I take Ashwagandha and Solifenacin together?

Why this happens

Both substances can affect the central nervous system. Ashwagandha is thought to have GABAergic (calming) effects, while solifenacin is an anticholinergic medication. When used together, their combined effects may lead to increased sleepiness or blurred vision. Additionally, ashwagandha may slightly influence the liver enzymes (CYP3A4) that break down solifenacin, potentially leading to higher levels of the medicine in your body.

What you should do

Use caution if combining these two. If you notice excessive sleepiness, severe dry mouth, constipation, or blurred vision, stop taking the ashwagandha and consult your doctor or pharmacist. It is best to start with a low dose of ashwagandha to see how your body reacts while taking solifenacin.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.