Can I take Doxazosin and Furosemide together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking these two medicines together can cause your blood pressure to drop too low, especially when you stand up. This might make you feel dizzy, lightheaded, or like you are going to faint.
In this article:
Continue reading below
Why this happens
Both medicines work to lower blood pressure but in different ways. Doxazosin relaxes your blood vessels, while furosemide (a 'water tablet') removes excess fluid from your body. When used together, their effects add up, which can lead to an excessive drop in blood pressure.
What you should do
Be careful when getting up from a sitting or lying position; move slowly to give your body time to adjust. Your doctor may want to monitor your blood pressure more closely or adjust your doses when starting this combination. If you feel very dizzy or faint, sit or lie down immediately and contact your doctor.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Bisoprolol and Trimbow pmdi // pressurised inhalation together?
Bisoprolol and Trimbow (which contains formoterol) work in opposite ways on the airways. Bisoprolol may cause the airways to narrow, making it harder to breathe and potentially triggering asthma or COPD symptoms. It also makes the formoterol in the Trimbow inhaler less effective at opening your airways.

Treatment and medication
Can I take Idapamide and Ramipril together?
Taking indapamide and ramipril together can cause your blood pressure to drop too low, especially when you first start the combination. This can make you feel dizzy, lightheaded, or faint. It can also put extra strain on your kidneys.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.