Can I take Farixca and Sabutril together?

Why this happens

Forxiga (dapagliflozin) is an SGLT2 inhibitor that works by removing sugar and water through your urine. Sacubitril (found in Entresto) is a neprilysin inhibitor that also has a mild diuretic (water-clearing) effect. When used together, they can cause the body to lose too much fluid and salt, leading to low blood pressure or dizziness. Additionally, sacubitril can affect potassium levels, which requires monitoring when your kidney function is also being affected by a diuretic effect.

You can take these medicines together, as they are often prescribed together for heart failure, but you must be monitored closely by your doctor. Ensure you stay well-hydrated and tell your doctor if you feel very dizzy, lightheaded when standing up, or if you notice a significant change in how much you are urinating. Your doctor will likely perform regular blood tests to check your kidney function and potassium levels.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.