Can I take Glucosamine and Vitamin b12 together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There are no known clinical interactions between glucosamine and vitamin B12. It is generally considered safe to take these two supplements together.
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Why this happens
Glucosamine and vitamin B12 are processed by the body through different pathways. Glucosamine is an amino sugar used by the body to build cartilage, while vitamin B12 is a water-soluble vitamin involved in nerve function and red blood cell production. They do not interfere with each other's absorption, metabolism, or effectiveness.
What you should do
You can continue to take both supplements as directed by your healthcare provider or the product packaging. As with any supplement, if you notice any unusual side effects, consult your pharmacist or doctor.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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