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Can I take Ibuprofen gel 10% and Quinine together?

Drug interaction guide

There is no known direct interaction between ibuprofen gel and quinine. Because the ibuprofen is applied to the skin as a gel, very little of the medicine reaches your bloodstream compared to taking a tablet. This makes an interaction with quinine extremely unlikely.

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Why this happens

Ibuprofen gel works locally on the area where it is applied. Quinine is processed by the liver and kidneys. Since the amount of ibuprofen absorbed into the system from a gel is very low, it does not interfere with how quinine works or how the body breaks it down.

What you should do

It is generally safe to use these two together. However, if you have a history of kidney problems, stomach ulcers, or asthma, you should still check with your pharmacist before using any form of ibuprofen, including gels.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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