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Can I take Losartan and Vitamin b12 together?

Drug interaction guide

There is no known interaction between losartan and vitamin B12. It is generally safe to take these two together.

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Why this happens

Losartan is a blood pressure medication (angiotensin II receptor blocker) and vitamin B12 is a water-soluble vitamin. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness.

What you should do

You can continue taking both as prescribed. As with any supplement, it is always a good idea to inform your doctor or pharmacist about everything you are taking to ensure your records are up to date.

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Important precautions

Pregnancy

You must not take this medicine if you are pregnant or planning to become pregnant. It can cause serious harm or death to an unborn baby, particularly if used during the second and third trimesters.

High potassium levels (Hyperkalaemia)

Avoid using salt substitutes containing potassium or taking potassium supplements while on this medicine, as it can cause your potassium levels to become dangerously high.

Food and drink warnings

Potassium-rich foods (e.g., bananas, spinach, avocados) and salt substitutes

Losartan can increase the levels of potassium in your blood. Consuming large amounts of potassium-rich foods or using salt substitutes containing potassium can lead to dangerously high potassium levels (hyperkalaemia).

Alcohol

Drinking alcohol while taking losartan can increase the medicine's blood-pressure-lowering effect. This may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep alcohol intake to a minimum until you know how the medicine affects you.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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