Can I take Magnesium and St john's wort together?

Why this happens

Magnesium and St John's Wort are processed by the body through different pathways. Magnesium is a mineral primarily regulated by the kidneys, while St John's Wort affects liver enzymes (specifically CYP3A4). They do not interfere with each other's absorption or effectiveness.

What you should do

You can take these together. However, always inform your doctor or pharmacist about all supplements you are taking, as St John's Wort interacts with many prescription medicines (such as antidepressants, blood thinners, and the contraceptive pill).

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.