Can I take Paracetamol and Rosuvastatin together?

Why this happens

Paracetamol and rosuvastatin are processed by different pathways in the liver and do not interfere with how the body absorbs, breaks down, or removes either drug.

What you should do

You can take paracetamol while you are on rosuvastatin. Always follow the dosage instructions on the packet for paracetamol and do not exceed the maximum daily dose. If you experience unusual muscle pain, tenderness, or weakness while taking rosuvastatin, you should contact your doctor, regardless of whether you are taking paracetamol.

Important precautions

Pregnancy

You must not take rosuvastatin if you are pregnant or planning to become pregnant, as it may harm the unborn baby. Use effective contraception while taking this medicine.

Liver health and multiple medications

Taking more than the recommended dose, or taking paracetamol with other products that also contain it (such as cold and flu remedies), can cause life-threatening liver damage. Always check the labels of all medicines you are taking.

Unexplained muscle pain - rosuvastatin

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, as this can rarely lead to serious kidney problems.

Food and drink warnings

Alcohol

It is best to avoid or strictly limit alcohol when taking paracetamol. Combining alcohol and paracetamol increases the risk of serious liver damage.

Drinking large amounts of alcohol while taking rosuvastatin can increase your risk of developing serious liver problems. It is best to avoid excessive drinking (binge drinking) and stay within the recommended weekly limits.

Grapefruit juice

Unlike some other statins, rosuvastatin is not significantly affected by grapefruit juice. You can consume it in normal amounts, though it is always best to avoid drinking very large quantities (more than a litre a day).

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.