Can I take Quinine and Shortec together?

Why this happens

Quinine can interfere with the way your liver breaks down oxycodone (by affecting an enzyme called CYP3A4). This causes the oxycodone to stay in your system longer and reach higher levels. Additionally, both drugs can slow down the central nervous system, leading to a combined (additive) effect on your breathing and alertness.

What you should do

You should speak to your doctor before taking these two medicines together. If your doctor confirms you need both, they may need to adjust your dose. Seek immediate medical help if you experience extreme drowsiness, confusion, shallow breathing, or if you find it difficult to wake up.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.