Mizolastine tablets
Mizollen (discontinued)
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 15 Jan 2025
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Clinical author's note Michael Stewart 15/01/2025: Mizollen® tablets were discontinued in the UK in October 2024. At the time of review there are no branded or generic products containing mizolastine available in the UK. Mizolastine may still be available in other countries. This medicine leaflet is based on medical information accessed in the UK at the time of writing and is left here for reference purposes. Please also refer to the manufacturer's information supplied with your medicine.
Mizolastine relieves allergic symptoms.
Take one tablet daily.
Mizolastine is called a non-drowsy antihistamine; however, it can still cause drowsiness in a few people. Make sure your reactions are normal before you drive, or before using tools or machines.
At a glance
Mizolastine is an antihistamine medicine used for allergies like hay fever and urticaria.
It works by blocking histamine, which reduces allergy symptoms such-as sneezing, runny nose, and itchy rash.
The usual dose is one tablet daily for adults and children over 12 years.
Mizolastine is a non-drowsy antihistamine, but some people may still feel sleepy or dizzy.
Do not drive or operate machinery if you feel drowsy after taking mizolastine.
Tell your doctor if you are pregnant, breastfeeding, or have certain health conditions before taking it.
In this article:
Continue reading below
About mizolastine
Type of medicine | An antihistamine (non-drowsy) |
Used for | Allergies such as hay fever and some allergic skin reactions |
Also called | Mizollen® (discontinued) |
Available as | Tablets |
Mizolastine is an anti-allergy medicine. It stops the effects of a substance called histamine and this helps to relieve the symptoms of allergies such as hay fever and urticaria.
Exposure to substances such as pollen, animal fur or house dust mite can cause your body to produce allergic symptoms. Cells in the lining of your nose release histamine when they come into contact with these substances. This leads to inflammation (rhinitis), which produces symptoms such as sneezing and a runny or blocked nose.
Urticaria is a condition where an itchy skin rash develops. The rash may be triggered by an allergy or it can be caused by some other factor which may not be known.
Before taking mizolastine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking mizolastine it is important that your doctor knows:
If you are pregnant or breastfeeding.
If you have any problems with the way your liver works.
If you have a heart condition or an abnormal heart rhythm.
If you have epilepsy.
If you have a rare inherited blood disorder called porphyria.
If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
If you have ever had an allergic reaction to another antihistamine, or to any other medicine.
Continue reading below
How to take mizolastine
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about mizolastine, and will also provide you with a full list of side-effects which you could experience from taking it.
The usual dose for adults and children over 12 years, is one tablet (10 mg) daily. Swallow the tablet whole (without chewing or crushing it) with a drink of water.
You can take mizolastine at whatever time of day you find easiest to remember, but try to take your doses at the same time of day each day. You can take the tablet either before or after a meal.
If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day then leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.
Getting the most from your treatment
Many people only need to take an antihistamine when they have symptoms. Unless you are told otherwise, you should stop taking mizolastine once your symptoms have eased.
Although mizolastine is classed as a non-drowsy antihistamine, it can still cause drowsiness in a few people. If this happens to you, do not drive and do not use tools or machines.
If you drink alcohol while you are on mizolastine, be aware of its effects on you and do not drink more than moderate amounts. Alcohol can increase the risk of side-effects from antihistamines.
If you are having an operation, or any treatment or tests (particularly if it is to test for an allergy), make sure you say that you are taking an antihistamine.
If you buy any medicines 'over the counter', check with a pharmacist that they are suitable to take with an antihistamine. This is because a number of other medicines can increase the risk of side-effects.
Continue reading below
Can mizolastine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with mizolastine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.
Common mizolastine side-effects (these affect fewer than 1 in 10 people) | What can I do if I experience this? |
Feeling sleepy or dizzy, lack of energy | If this happens, do not drive and do not use tools or machines while affected |
Dry mouth | Try chewing sugar-free gum or sucking sugar-free sweets |
Feeling sick (nausea), indigestion, tummy (abdominal) pain | This should soon pass but in the meantime avoid rich or spicy food |
Diarrhoea | This should soon pass but in the meantime drink plenty of water |
Headache | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
Increased appetite and weight | Eat a well-balanced diet |
If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.
How to store mizolastine
Keep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Important information about all medicines
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.

Unsure about mixing medicines?
Check for possible interactions between medicines, supplements and foods before taking them together.
Frequently asked questions
Can children take mizolastine?
Mizolastine is suitable for adults and children over 12 years of age. The usual dose for this age group is one 10 mg tablet daily.
What should I do if mizolastine makes me feel drowsy, even though it's non-drowsy?
Although mizolastine is typically a non-drowsy antihistamine, a small number of people may still experience drowsiness. If you feel sleepy or drowsy after taking it, you should avoid driving or operating tools and machinery to ensure your safety.
Will mizolastine interact with my other medications?
When starting mizolastine, it's important to inform your doctor about all other medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. This is because some medicines can increase the risk of side-effects when taken with an antihistamine.
What should I do if I get a dry mouth from taking mizolastine?
Dry mouth is a common side-effect of mizolastine. To help relieve this, you can try chewing sugar-free gum or sucking on sugar-free sweets.
If my allergic symptoms disappear, should I keep taking mizolastine?
Generally, you only need to take an antihistamine like mizolastine when you have symptoms. Unless your doctor has specifically advised you to continue, you can stop taking the medication once your symptoms have eased.
Further reading and references
- Medicines Complete BNF 89th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Continue reading below
About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 15 Jan 2028
15 Jan 2025 | Latest version

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