Epididymal Cyst

Authored by , Reviewed by Dr Colin Tidy | Last edited | Meets Patient’s editorial guidelines

An epididymal cyst is a harmless fluid-filled growth on a man's testicle (testis). They are quite common and don't usually require treatment. Many men feel them and are concerned they have testicular cancer, but a doctor can usually tell the difference.

A cyst is just any small bulge that is filled with fluid. Cysts can grow almost anywhere in the body.

The epididymis is the name of the little tubes just above the testicle (testis). This picture shows where the epididymis is:

Cross-section view

Cross-section diagram of a testis

So an epididymal cyst is a harmless growth that grows from the tubes just around a man's testicle.

Men are most likely to develop these cysts during middle age. Children rarely get them before they become teenagers. It's hard to give an exact percentage of boys or men who have epididymal cysts because most people who have them don't know that they do.

  • A soft, slightly squidgy lump at the top or bottom of your testicle (testis).
  • They are usually entirely pain-free.
  • They do not get infected or affect your ability to pass urine or to ejaculate.

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  • Inflammation: some illnesses cause a thickening of the epididymis and surrounding structures which can feel like an epididymal cyst.
  • Hydrocele: this is caused by a collection of fluid in the scrotum.
  • Varicocele: this is like varicose veins of the small veins next to one testicle (testis) or both testes. It is usually described as feeling like a 'wriggling bag of worms'.
  • Lipoma: this is a fatty lump which can sometimes cause difficulty because it can be felt separate from the testicle, just like an epididymal cyst.
  • Usually they are quite typical in the way they feel and a doctor can confidently reassure you.
  • If the doctor isn't quite sure what the lump is, they could arrange an ultrasound scan of your scrotum. 

Most men with epididymal cysts are quite healthy. There are some quite rare conditions that are associated with epididymal cysts:

  • Cystic fibrosis: an inherited illness in which there are cysts in the lungs, pancreas and other areas of the body.
  • Polycystic kidney disease: an inherited condition in which cysts develop in the kidneys and other parts of the body.

Males who have epididymal cysts are not at increased risk of infertility if they are otherwise well.

  • If the cyst is small and causing no problems then all you need to do is keep an eye on it and see a doctor if it gets bigger or painful.
  • Children do not usually need treatment because most cysts disappear by themselves. However it may take up to four years to resolve. Surgical removal may be necessary if they become painful or don't start to shrink.
  • Large or painful cysts can be surgically removed or treated by aspiration and injection of a substance to shrink and seal the cyst.
  • Usually epididymal cysts don't cause any problems at all. But occasionally they can twist around and become very painful. This is called torsion and happens pretty quickly: within about half an hour. It is really painful and usually needs surgery to untwist it and remove it.

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Further reading and references

  • Low LS, Nair SM, Davies AJW, et al; Aspiration and sclerotherapy of hydroceles and spermatoceles/epididymal cysts with 100% alcohol. ANZ J Surg. 2020 Jan90(1-2):57-61. doi: 10.1111/ans.15467. Epub 2019 Oct 18.

  • Weatherly D, Wise PG, Mendoca S, et al; Epididymal Cysts: Are They Associated With Infertility? Am J Mens Health. 2018 May12(3):612-616. doi: 10.1177/1557988316644976. Epub 2016 Apr 26.

  • Mukendi AM; Bilateral epididymal cyst with spontaneous resolution. Clin Case Rep. 2020 Aug 228(12):2689-2691. doi: 10.1002/ccr3.3199. eCollection 2020 Dec.

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