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Can I take Atorvastatin and Royal sun together?

Drug interaction guide

Taking Royal Sun (Agaricus blazei) alongside atorvastatin may increase the risk of liver irritation or damage. Both substances are processed by the liver, and there have been rare reports of this mushroom causing liver inflammation (hepatitis). Combining them could potentially put extra strain on your liver.

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Why this happens

Both atorvastatin and Royal Sun mushroom can affect liver enzymes. While atorvastatin is a well-known cause of rare liver side effects, Royal Sun contains compounds that have been linked to liver toxicity in some case studies. Taking them together may have an additive effect on liver stress.

What you should do

Use caution when combining these two. Before starting Royal Sun, you should speak with your doctor or pharmacist. If you decide to take both, watch out for signs of liver problems, such as yellowing of the eyes or skin (jaundice), dark urine, or pain in the upper right side of your stomach. Your doctor may want to perform routine blood tests to check your liver function.

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Using other medicines?

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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