Can I take Diazepam and Paracetamol together?

Why this happens

These drugs are processed by different pathways in the liver and do not interfere with how the other is absorbed, broken down, or removed from the body. They also work on different parts of the nervous system.

What you should do

You can take these medicines together as prescribed or directed on the packaging. Always follow the recommended dose for each. If you feel unusually drowsy, avoid driving or using machinery.

Important precautions

Alcohol consumption

Do not drink alcohol while taking diazepam. Combining them can cause dangerously shallow breathing, extreme sleepiness, and can be fatal.

Liver health and multiple medications

Never exceed the maximum dose (usually 8 tablets in 24 hours). Many cold and flu remedies also contain paracetamol; taking them together can cause fatal liver damage.

Long-term use and dependency

Diazepam is for short-term use only (usually 2-4 weeks). Using it longer can lead to physical addiction and severe withdrawal symptoms if stopped suddenly.

Food and drink warnings

Alcohol

You must not drink alcohol while taking diazepam. Alcohol increases the sedative effects of the medicine, which can lead to extreme sleepiness, dangerous breathing problems, and loss of consciousness.

Grapefruit juice

Avoid drinking grapefruit juice or eating grapefruit. It can increase the amount of diazepam in your blood, making side effects like drowsiness more likely and longer-lasting.

Caffeine (Coffee, Tea, Energy Drinks)

Caffeine can reduce the calming effects of diazepam because it acts as a stimulant, which works against the medicine's purpose.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.