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Can I take Maitake and Royal sun together?

Drug interaction guide

Both Maitake (Grifola frondosa) and Royal Sun (Agaricus blazei) mushrooms can lower blood sugar levels and thin the blood. Taking them together may increase the risk of your blood sugar dropping too low (hypoglycaemia) or increase the risk of bruising and bleeding.

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Why this happens

These mushrooms have 'additive' effects. This means they work in similar ways to lower glucose and inhibit blood platelets from sticking together. When combined, their individual effects are added together, making the overall impact on your body stronger.

What you should do

If you choose to take both, monitor your blood sugar levels closely, especially if you have diabetes. Watch for signs of low blood sugar, such as feeling shaky, sweaty, or dizzy. You should also be careful if you are taking blood-thinning medications or have an upcoming surgery. It is best to discuss the use of multiple medicinal mushrooms with your doctor or a pharmacist.

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Using other medicines?

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 24 Jan 2026 | Originally published
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