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Can I take Biotin and Tamoxifen together?

Drug interaction guide

There is no known direct interaction between biotin and tamoxifen that would change how the medication works or increase side effects. However, high doses of biotin can interfere with certain blood tests used to monitor your health while taking tamoxifen.

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Why this happens

Biotin does not change how tamoxifen is absorbed, broken down, or used by the body. However, biotin is often used in laboratory testing technology. Taking high doses of biotin can cause 'false' results in hormone tests (like oestrogen or thyroid tests) and tumour marker tests, which your doctor may use to monitor your treatment.

What you should do

It is generally safe to take these together. However, you must tell your doctor and the laboratory staff that you are taking biotin before having any blood tests. Most experts recommend stopping biotin supplements at least 48 to 72 hours before a blood test to ensure the results are accurate.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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