Can I take Ibuprofen gel 10% and Oxypro together?

Why this happens

Oxycodone is an opioid painkiller that slows down the central nervous system. Ibuprofen is an anti-inflammatory (NSAID). When used together, they can have an additive effect on the body, potentially increasing drowsiness. Although the gel is applied to the skin, a small amount enters the system and can interact with the way oxycodone affects the body and the stomach lining.

What you should do

It is generally safe to use these together for short periods, but you should use the ibuprofen gel sparingly. If you feel excessively sleepy, dizzy, or develop stomach pain, stop using the gel and speak to your doctor. Avoid drinking alcohol while using these medicines, as it will make the drowsiness much worse.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.